A recent study that looked at the results of children who underwent deep anterior lamellar keratoplasty (DALK) surgery over an eight-year period concluded that manual dissection DALK is a safe procedure in children with stromal opacities.

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The research reviewed the records of 42 pediatric patients, most with mucopolysaccharidosis or keratoconus who underwent DALK surgery between January 2007 and January 2015. The researchers compiled data collected including preoperative and postoperative spectacle-corrected distance visual acuity (CDVA), intraoperative and postoperative complications including graft rejection and failure as well as residual posterior lamellar thickness (RPLT) and endothelial cell density (ECD).

DALK is often femtosecond laser-assisted to produce regular, smooth cutting surfaces that facilitate the separation of the anterior stroma and enhance the adherence between the recipient and donor tissue. The Femto laser is also used for trephination of the donor graft, according to precisely personalized diameter and profile parameters.

The results of the study are noted in the British Journal of Ophthalmology.